Abcam, ab323240, Anti-IL-1 beta antibody [EPR23851-127] – Chicken IgY (Chimeric)

Size: 20µL / 100µL / 1mL
Chicken Recombinant Monoclonal IL-1 beta antibody. Suitable for ICC/IF and reacts with Human, Mouse, Rat samples.
Key facts
Host species:Chicken,
Clonality:Monoclonal,
Clone number:EPR23851-127,
Isotype:IgY,
Carrier free:No,
Reacts with:Human, Mouse, Rat,
Applications:ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:IL-1 beta is not present under homeostatic conditions and it is induced and secreted only upon inflammatory signals. Stimulation may be required for the detection of IL-1β as it is not constitutively expressed no matter in precursor or mature form. For example when using ab254360 positive signal can be detected in RAW264.7 with 100 ng/ml LPS treatment for 7h and additional 300 ng/ml Brefeldin A treatment in the last 3h. IL-1β is a secreted protein it is recommended to treat cells with anti-secretion reagents (eg. Brefeldin A) that inhibit secretion.FURTHER INFORMATION ON SPECIFICITY (Chinese Version) available under the Product Protocol section.

Product details:
This chicken monoclonal chimeric antibody has been engineered from a RabMAb parent antibody (
ab254360
). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended.
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Thiophilic Resin, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle