Abcam, ab35835, Anti-Pseudomonas aeruginosa antibody [B11]

Size: 100µg
Mouse Monoclonal Pseudomonas aeruginosa antibody. Suitable for ELISA and reacts with Pseudomonas aeruginosa samples. Cited in 4 publications.
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:B11,
Isotype:IgG2a,
Carrier free:No,
Reacts with:Pseudomonas aeruginosa,
Applications:ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4Preservative: 0.09% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Pseudomonas aeruginosa is a versatile gram-negative bacterium often referred to as "P. aeruginosa." It has a mass of approximately 6 million Daltons and is known for its motility which is enabled by flagella and type IV pili. This bacterium is commonly found in soil water and healthcare settings. It exhibits an ability to express various virulence factors such as exotoxins elastase and pyocyanin which contribute to its pathogenicity.
Biological function summary
The mechanisms of Pseudomonas aeruginosa involve adaptation and survival in diverse environments. This adaptability is enhanced by its presence in complex biofilms structures that provide protection against hostile conditions including antimicrobial agents. Biofilm formation involves a multitude of genes and contributes to its persistence especially in hospital environments where it can colonize medical devices and surface.
Pathways
The adaptability of Pseudomonas aeruginosa is supported by its involvement in the quorum-sensing pathway. This cell-to-cell communication mechanism regulates gene expression related to virulence and biofilm formation. The bacterium also participates in the type VI secretion system pathway interacting with proteins associated with bacterial competition and host interactions allowing it to invade and persist within host tissues.
Pseudomonas aeruginosa is a significant pathogen in nosocomial infections and chronic pulmonary conditions such as cystic fibrosis. The bacterium's expression of proteins including elastase and alkaline protease damages host tissues and impairs immune responses. Its ability to form biofilms relates closely to the chronic nature of infections and resistance to treatment complicating disease management and therapy.