Abcam, ab55841, Anti-CYPIVF11 antibody [F21 P6 F5]

Size: 100µg
Mouse Monoclonal CYPIVF11 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human CYP4F11.
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:F21 P6 F5,
Isotype:IgG1,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human CYP4F11. The exact immunogen used to generate this antibody is proprietary information.Q9HBI6

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Storage buffer-Preservative: 0.08% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
CYPIVF11 also known as Cytochrome P450 Family 4 Subfamily F Member 11 functions as a monooxygenase enzyme involved in the oxidation of organic substances. It plays a role in drug metabolism and the synthesis of cholesterol steroids and other lipids. The enzyme has a mass of approximately 54 kDa. CYPIVF11 is predominantly expressed in hepatic tissues where it contributes to metabolic processes.
Biological function summary
CYPIVF11 mediates the oxidative breakdown of fatty acids. It participates in epoxygenation reactions and helps to convert long chain fatty acids into metabolites that are used by the body. CYPIVF11 might interact with other cytochrome P450 enzymes forming a complex network that enhances broad substrate specificity and metabolic capacity.
Pathways
CYPIVF11 engages in the arachidonic acid metabolism and the fatty acid degradation pathways. It associates with proteins such as CYP4A11 and CYP4F2 within these pathways contributing to the modulation of inflammatory responses by converting arachidonic acid into bioactive lipid mediators. This function connects it closely with lipid homeostasis and energy metabolism.
Aberrant expression or function of CYPIVF11 links to cardiovascular diseases and liver disorders. Its role in lipid metabolism relates it to the inflammatory pathways that are often upregulated in atherosclerosis. Through interactions with proteins like CYP4F12 it has implications in the development of liver pathologies associated with impaired detoxification processes.