Abcam, ab62385, Anti-Mycoplasma bovis antibody [MY11-320.1]

Size: 250µg
Mouse Monoclonal Mycoplasma bovis antibody. Carrier free. Suitable for ELISA and reacts with Mycoplasmopsis bovis samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing Mycoplasma bovis protein.
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:MY11-320.1,
Isotype:IgG1,
Carrier free:Yes,
Reacts with:Mycoplasmopsis bovis,
Applications:ELISASee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Storage buffer-pH: 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Mycoplasma bovis also known as M. bovis is a bacterial pathogen that affects cattle. It belongs to the Mycoplasmataceae family and this organism lacks a cell wall which is unusual among bacteria. The genome size is approximately 1.08 million base pairs. M. bovis can be found in the respiratory and urogenital tracts of the host animals. This pathogen interacts with cattle cells by adhering to the epithelial cells which allows it to evade the host's immune system and cause persistent infections.
Biological function summary
The actions of Mycoplasma bovis lead to significant disruptions in the host's physiological processes. It forms large complexes with host proteins to interfere with normal cell functions and to aid in immune evasion. The organism is a known contributor to the development of infectious respiratory diseases in cattle. M. bovis also secretes enzymes and exotoxins which further lesion host tissues contributing to disease pathology.
Pathways
Mycoplasma bovis affects several significant biological processes in cattle. It plays an important role in the inflammatory response and immune system pathways. The invasion and modulation strategies of M. bovis interact with immune regulatory proteins like toll-like receptors which can alter signaling cascades and lead to chronic inflammation. These pathways contribute to the pathogen's ability to persist and cause long-term infections.
Mycoplasma bovis is associated primarily with bovine respiratory disease (BRD) and mastitis. The pathogen's interaction with host immune proteins such as cytokines exacerbates these conditions. Infection with M. bovis complicates and worsens BRD by damaging lung tissues and promoting secondary bacterial infections. In mastitis M. bovis disrupts the normal defense mechanisms of mammary glands which results in reduced milk production and quality affecting the dairy industry severely.