Abcam, ab69564, Anti-CAMKV antibody

Size: 100µg
Rabbit Polyclonal CAMKV antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human CaM kinase-like vesicle-associated protein.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC/IF, WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human CaM kinase-like vesicle-associated protein. The exact immunogen used to generate this antibody is proprietary information.Q8NCB2

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
CAMKV also known as CaM kinase-like vesicle-associated protein plays a role in cellular signaling. This protein has an approximate mass of 38 kDa. It is expressed in the brain suggesting its potential importance in neural processes. CAMKV possesses structural similarities with the family of calcium/calmodulin-dependent protein kinases although its exact kinase activity remains uncertain.
Biological function summary
CAMKV contributes to neuronal functioning and development impacting processes such as synaptic plasticity and dendritic spine morphology. CAMKV might associate with protein complexes that regulate these neuronal processes providing structural support rather than catalytic action. Its involvement in synaptic functions indicates a role in optimizing signal transduction and maintaining neural connectivity.
Pathways
CAMKV impacts intracellular signaling networks that are important for brain development and synaptic plasticity. It is involved in the calcium signaling pathway and may interact with proteins like CaMKII or calmodulin to modulate calcium-mediated responses. This interaction helps manage calcium ions' flow affecting neuronal excitability and transmission.
CAMKV connects to neurological conditions like autism spectrum disorder and schizophrenia. Altered expression or dysfunction of CAMKV may intersect with proteins such as CaMKII and calmodulin which are also implicated in these disorders. Understanding CAMKV's role in these diseases could identify new therapeutic targets and strategies.