Abcam, ab79823, Anti-HMGB1 antibody [EPR3507]

Size: 100µL / 1mL
Anti-HMGB1 antibody [EPR3507] (ab79823) is a rabbit monoclonal antibody detecting HMGB1 in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IHC-P, ICC/IF . Suitable for Human, Mouse, Rat . - KO validated for confirmed specificity - Biophysical QC for unrivalled batch-batch consistency - Over 270 publications - Trusted since 2009
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR3507,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:IHC-P, WB, ICC/IF, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Anti-HMGB1 antibody [EPR3507] (ab79823) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB.
Anti-HMGB1 antibody [EPR3507] (ab79823) was first used in a scientific publication in 2011 and has been cited over 275 times in peer reviewed journals. It's performance in Western Blot in human, mouse and rat samples is trusted by the scientific community.
Abcam's high quality manufacturing and validation processes ensure Anti-HMGB1 antibody [EPR3507] (ab79823) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
The specificity of Anti-HMGB1 antibody [EPR3507] (ab79823) has been confirmed by Western Blot testing in HMGB1 knockout HeLa cells (
ab255395
Anti-HMGB1 antibody [EPR3507] (ab79823) has 7 independent reviews from customers.
Anti-HMGB1 antibody [EPR3507] (ab79823) specifically detects HMGB1 (UniProt ID: P09429; Molecular weight: 25kDa) and is sold in 100 µL and 1 mL selling sizes.
Conjugation-ready, carrier free format available for antibody clone EPR3507 -
ab216986
Antibody clone EPR3507 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor
488, Alexa Fluor
647, HRP, Alexa Fluor
594, Alexa Fluor
405, Alexa Fluor
555, APC, PE (
ab195010
ab195011
ab195012
ab206894
ab206895
ab206896
ab225041
ab225042
HMGB1 promotes inflammation and tissue damage in diseases like sepsis, cancer and autoimmune disorders by acting as a damage-associated molecular pattern (DAMP) and activating immune responses.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Stable for 12 months at -20°C