Abcam, ab91574, Anti-OCIAD1 antibody

Size: 100µg
Rabbit Polyclonal OCIAD1 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human OCIAD1.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human OCIAD1. The exact immunogen used to generate this antibody is proprietary information.Q9NX40,
Specificity:This antibody will not crossreact with OCIAD2.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
OCIAD1 also known as ovary carcinoma-associated disintegrin-domain containing protein 1 is a protein with a mass of approximately 35 kDa. It is expressed in various tissues with high levels observed in the ovaries and the central nervous system. Structurally OCIAD1 contains domains that may influence cellular interactions and signal transduction. Studies suggest that OCIAD1 influences cellular processes by participating in membrane-associated complexes which could be important for its mechanical roles.
Biological function summary
OCIAD1 engages in cellular signaling and regulation. It might be a part of a protein complex that contributes to cellular adhesion and proliferation. OCIAD1 appears to support cellular growth and may steer certain cell developmental pathways. By interacting with other proteins it could modulate cellular response mechanisms suggesting its importance in maintaining normal cellular function.
Pathways
OCIAD1 plays roles that impact the PI3K/AKT signaling pathway and the MAPK/ERK pathway. These pathways are essential for the regulation of cell survival growth and differentiation. Within these networks OCIAD1 may interact with proteins like AKT1 and ERK2 facilitating signal transduction that drives cellular responses. Its involvement in these pathways indicates a role in the modulation of critical intracellular signaling events.
OCIAD1 has an established link with ovarian cancer and neurodegenerative diseases such as Alzheimer's disease. In ovarian cancer OCIAD1 might contribute to the malignant transformation and tumor progression possibly in connection with proteins such as p53. In Alzheimer's disease altered OCIAD1 expression could affect proteins like tau which plays a significant role in neurofibrillary tangles. These associations suggest OCIAD1 as a potential target for therapeutic interventions in these conditions.