Abcam, ab93801, Anti-CEE antibody

Size: 100µL
Rabbit Polyclonal CEE antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human GET4 aa 250 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human GET4 aa 250 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q7L5D6

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 6.8 - 7.4Preservative: 0.09% Sodium azideConstituents: Tris buffered saline, 0.1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle, Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The protein CEE also known as CEEX1 plays an important mechanical role in cellular processes. It has a molecular mass of approximately 55 kDa and expresses in diverse tissue types including liver and brain. The protein interacts with cellular membranes performing functions integral to maintaining cellular structure and function.
Biological function summary
CEE influences cell signaling and metabolic processes. It functions within a larger protein complex regulating transcription factors critical in gene expression. This involvement allows CEE to influence adaptation and response mechanisms within the cell contributing to cellular homeostasis.
Pathways
The protein CEE participates in signal transduction and metabolic pathways. It interacts with kinase proteins like MAPK in the signaling pathway to mediate cell growth and survival. Through the metabolic pathway CEE supports various enzymatic activities linking it to the broader metabolic network within cells.
CEE plays a part in neurodegenerative diseases and cancer. Aberrations in CEE expression associate with Alzheimer's disease where it might affect tau protein phosphorylation. In cancer disrupted CEE activity links to abnormal cell proliferation often involving the protein p53 affecting tumor suppressor pathways.