Agilent, 5190-2510, Agilent Bio SEC-3, 150Å, 7.8 x 50 mm, 3 µm, guard

Agilent Bio SEC-3, 150Å, 7.8 x 50 mm, 3 µm, guard. A size exclusion guard column to protect and extend the lifetime of a longer analytical SEC column.

Specifications:
Brand: Agilent Bio SEC-3
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 7.8 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 80 °C
Molecular Weight Lower Limit: 500 Da
Molecular Weight Upper Limit: 150000 Da
Part Number Application Domain: Biopharma
Part Number Application: Aggregate & Fragment AnalysisPeptidesProteins
Particle Size: 3 µm
Particle Type: Fully Porous
Phase: SEC
Pore Size: 150 Å
Pressure Rating: 240 bar
Separation Mode: Size Exclusion (SEC)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-8.5

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Designed for advanced size exclusion chromatography of biomolecules, this Bio SEC-3 guard column features a 150 angstrom pore size, 7.8 x 50 mm dimensions, and 3 micron particle size. It provides superior resolution, fast analysis times, and robust protection for analytical columns handling proteins, antibodies, and other biotherapeutics. The guard column is ideal for routine screening in biopharmaceutical research, quality control, and method development labs requiring precise molecular weight distribution analysis.

Its optimized pore structure ensures reliable separation of small to mid-sized biomolecules while maintaining sample integrity and minimizing nonspecific interactions. This product is compatible with Agilent 1260 Infinity II, 1290 Infinity II, and earlier Infinity LC systems, as well as a wide range of HPLC and UHPLC platforms. For extended column performance, it pairs with Agilent’s Bio SEC-3 analytical columns. Seamless integration and easy installation facilitate high-throughput workflows without sacrificing data quality.

This solution is widely used in applications such as aggregate and fragment analysis, protein profiling, and characterization of monoclonal antibodies. Its robust design extends column life by trapping contaminants, reducing downtime, and supporting accurate, reproducible chromatographic results across various applications in biotechnology and life science research.