Agilent, 683775-913, AdvanceBio Glycan Mapping 120Å, 2.1 x 150 mm, 2.7 µm

AdvanceBio Glycan Mapping 120Å, 2.1 x 150 mm, 2.7 µm. This column has superficially porous particles with amide HILIC chemistry for high resolution at <600 bar pressure.

Specifications:
Brand: AdvanceBio Glycan Mapping
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 150 mm
Maximum Temperature: 40 °C
Part Number Application: Glycan Analysis
Part Number Application Domain: Biopharma
Particle Size: 2.7 µm
Particle Type: Superficially Porous
Phase: Amide HILIC
Pore Size: 120 Å
Pressure Rating: 600 bar
Separation Mode: HILIC
Shipping Solvent: Acetonitrile/Water
Technique: LC & LC/MS
UNSPSC Code: 41115711
pH Range: 2-7

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The AdvanceBio Glycan Mapping column with a 120 angstrom pore size, measuring 2.1 x 150 mm and featuring 2.7 micron particle size, is designed for high-resolution glycan analysis via liquid chromatography. Engineered for reliability and reproducible results, this column supports robust separation of glycans released from biotherapeutic proteins, monoclonal antibodies, and other glycoproteins. Its optimized stationary phase enables clear glycan profiling and structural elucidation, making it ideal for quality control, method development, and biopharmaceutical research laboratories.

Compatible with UHPLC and HPLC systems, including Agilent 1200 Infinity Series and similar platforms, this column ensures fast separations and high sensitivity. It is suitable for both fluorescence and mass spectrometry detection when coupled with appropriate front-end sample preparation and labeling strategies. Typical applications include glycosylation characterization, batch-to-batch comparability, and monitoring of critical quality attributes during the development and manufacturing of biologic drugs.

The product is part of the broader AdvanceBio family, which offers complementary columns for protein, peptide, and oligonucleotide analyses, facilitating comprehensive biomolecule characterization. Its high performance, durability, and compatibility with leading instruments make it an essential tool for scientists focused on detailed glycan mapping in regulated environments.