Agilent, 787775-906, AdvanceBio RP-mAb SB-C8, 2.1 x 75 mm, 3.5 µm

AdvanceBio RP-mAb SB-C8, 2.1 x 75 mm, 3.5 µm. A reversed-phase C8 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for intact or subunit analysis of mAbs. StableBond technology ensures stability at low pH.

Specifications:
Brand: AdvanceBio RP mAb C8
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 75 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: SB-C8
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The AdvanceBio RP-mAb SB-C8, 2.1 x 75 mm, 3.5 µm column is specifically engineered for high-resolution reversed-phase analysis of monoclonal antibodies and related biomolecules. Featuring a C8 bonded phase, this column offers excellent selectivity and optimal retention for hydrophobic protein fragments, promoting accurate characterization and quantitation of both intact mAbs and subunits. Its robust silica support and precisely controlled particle size ensure high efficiency, reproducibility, and peak symmetry, making it a reliable choice for regulated biopharmaceutical workflows.

Ideal for reversed-phase liquid chromatography applications, this column is widely used in protein and peptide mapping, monitoring product quality, and assessing post-translational modifications. Its design supports complex analyses such as mapping of mAb variants and fragmentation products, contributing significantly to method development and validation in both research and quality control settings.

This column is fully compatible with Agilent InfinityLab LC Series and other major UHPLC and HPLC platforms, simplifying integration into existing laboratory workflows. It can be paired with AdvanceBio sample preparation kits and guard columns to further enhance analytical performance and column lifetime. Researchers and analytical scientists in the biopharmaceutical industry will find it especially suited for detailed characterization and robust routine analyses.