Agilent, 799975-904, AdvanceBio RP-mAb C4, 4.6 x 50 mm, 3.5 µm

AdvanceBio RP-mAb C4, 4.6 x 50 mm, 3.5 µm. A reversed-phase C4 HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins for intact or subunit analysis.

Specifications:
Brand: AdvanceBio RP mAb C4
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: C4
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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Engineered for high-performance reversed-phase chromatography, this column features a 4.6 x 50 mm format with 3.5 micrometer particle size, offering exceptional resolution and reproducibility for intact and subunit monoclonal antibody analysis. Its robust C4 bonded phase optimizes protein separation, providing excellent recovery and minimized carryover for large biomolecules. Researchers working in biopharmaceutical characterization, quality control, and process development benefit from rapid, reliable separation of mAbs and related biological therapeutics.

Ideal for use with UHPLC and HPLC systems, the column supports a wide range of mobile phases, accommodating diverse aqueous and organic solvent conditions critical in biopharma workflows. Its high pressure tolerance ensures compatibility with leading platforms, including Agilent 1290 Infinity II and other comparable systems. The column is also fully compatible with mass spectrometry when downstream characterization is required.

Designed for durability and consistent performance even under frequent sample loading, it streamlines workflows in both upstream discovery and downstream production environments. Consider pairing this column with AdvanceBio pre-columns and guard cartridges for extended lifetime and protection from sample impurities. Trust this analytical tool for accurate, high-throughput protein analysis in complex biological samples, supported by Agilent’s proven technology.