Agilent, GKC-005300, AdvanceBio A3 N-glycan standard (formerly ProZyme)

AdvanceBio A3 N-glycan standard (formerly ProZyme). N-glycan (asialo-, agalacto-, triantennary complex). Qualitative standard for glycan identification Alternative glycan name: NGA3.

Specifications:
Chemical Structure:
Label: Unlabeled
Monoisotopic Mass: 1519.566
Name: A3
Oxford Name: A3
Standard Type: Complex-type Native N-Glycan
Unit: 10 µg

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The AdvanceBio A3 N-glycan standard provides a high-quality reference for accurate profiling and quantitation of N-linked glycans in biopharmaceutical research and quality control. Designed to support reproducible method development and system suitability testing, this standard delivers a defined mixture of well-characterized N-glycan structures commonly observed in therapeutic antibodies and glycoproteins. Its integration into analytical workflows ensures precise retention time alignment and system calibration in LC and LC-MS analyses.

Ideal for laboratories engaged in glycan characterization, biosimilar development, and lot-to-lot consistency monitoring, this standard supports regulatory compliance by facilitating robust method validation. It enhances the reliability of analytical results when assessing product glycosylation patterns and detecting potential variations across manufacturing batches. The standard is fully compatible with Agilent AdvanceBio Glycan Mapping columns, as well as a wide range of HILIC UHPLC and LC-MS instruments. It may also be used alongside Agilent glycan labeling kits, such as the AdvanceBio Gly-X solutions, for streamlined sample preparation and increased workflow efficiency.

Researchers and quality assurance professionals benefit from its batch-to-batch consistency and traceable performance, making it an essential tool for critical decision-making in biologics development and release testing.