Agilent, GKC-035300, AdvanceBio G3 / A3G3 N-glycan Standard

AdvanceBio G3 / A3G3 N-glycan Standard. N-glycan (asialo-, galactosylated triantennary). Qualitative standard for glycan identification. Alternative glycan names: A3G(4)3, NA3.

Specifications:
Chemical Structure:
Label: Unlabeled
Monoisotopic Mass: 2005.7244
Name: G3
Oxford Name: A3G(4)3
Standard Type: Complex-type Native N-Glycan
Unit: 10 µg

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This N-glycan standard is designed for high-precision profiling and characterization of biotherapeutic monoclonal antibodies and other glycoproteins. The purified mixture contains well-characterized G3 and A3G3 neutral complex N-glycan structures, allowing researchers to confidently identify, assign, and quantify these glycans during method development or routine quality control. Compatible with HILIC and other glycan analysis workflows, this standard is ideal for laboratories employing liquid chromatography with fluorescence detection, mass spectrometry, or capillary electrophoresis.

It provides reliable retention time markers, assisting in the validation and calibration of analytical platforms such as Agilent AdvanceBio LC columns, including 2.1 mm and 4.6 mm HILIC columns. Used widely in the biopharmaceutical industry and academic research, it enables robust system suitability testing, method optimization, and monitoring of glycosylation patterns in biosimilars and innovator biologics. The standard integrates seamlessly into automated or manual sample preparation protocols, supporting traceable and reproducible glycan analysis workflows. For best results, use it with Agilent glycan labeling kits and data analysis software suites for streamlined identification and quantification across multiple instrument platforms. This standard enhances comparability, accuracy, and confidence in N-glycan analysis for drug development and glycoproteomics.