Agilent, GKC-046300, AdvanceBio G4 / A4G4 N-glycan Standard

AdvanceBio G4 / A4G4 N-glycan Standard. N-glycan (asialo-, galactosylated tetraantennary complex). Qualitative standard for glycan identification. Alternative glycan name: A4G(4)4, NA4

Specifications:
Chemical Structure:
Label: Unlabeled
Monoisotopic Mass: 2370.8566
Name: G4
Oxford Name: A4G(4)4
Standard Type: Complex-type Native N-Glycan
Unit: 10 µg

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This N-glycan standard provides a high-quality, well-characterized reference specifically designed for glycan analysis in biopharmaceutical development and quality control. It features a mixture of G4 and A4G4 species, widely recognized as essential controls in the profiling and quantitation of N-linked glycans released from therapeutic proteins and antibodies. Supplied in a ready-to-use format, it supports accurate system calibration and method validation in HPLC, UHPLC, and LC-MS workflows.

The standard is ideal for use in analytical laboratories focused on biosimilar development, lot release, or structural characterization studies, ensuring reliable and reproducible results. It facilitates precise retention time calibration and chromatographic system suitability testing when used with popular glycan labeling chemistries such as 2-AB, RapiFluor-MS, or other fluorescent or MS-compatible tags.

This product is fully compatible with Agilent AdvanceBio columns and seamlessly integrates into Agilent HPLC and LC-MS platforms, including the InfinityLab and 6545XT AdvanceBio LC/Q-TOF systems. It also works effectively with third-party instruments, making it suitable for a variety of analytical setups. By ensuring confidence in glycan profiling results, this standard supports regulatory compliance and streamlines workflow optimization in both research and routine quality assurance environments.