Agilent, GKC-224300, AdvanceBio G2S2 α(2,6) / A2G2S(6)2 N-glycan Standard

AdvanceBio G2S2 α(2,6) / A2G2S(6)2 N-glycan Standard. N-glycan (di-sialylated-, galactosylated biantennary complex). Qualitative standard for glycan identification. Alternative glycan names: G2S2, A2G(4)2S(6)2, A2.

Specifications:
Chemical Structure:
Label: Unlabeled
Monoisotopic Mass: 2222.783
Name: G2S2 (α2,6)
Oxford Name: A2G(4)2S(6)2
Standard Type: Complex-type Native N-Glycan
Unit: 10 µg

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This high-purity N-glycan standard is specifically designed to enable accurate and reproducible analysis in glycan profiling workflows. The standard contains the highly purified G2S2 α(2,6) glycan, also known as A2G2S(6)2, offering precise quantitation and retention time referencing for glycan structure assignments. Optimized for LC-FLD, LC-MS, and LC-MS/MS platforms, it assures robust compatibility with Agilent AdvanceBio Glycan Mapping columns, 1290 Infinity II LC systems, and other major analytical instruments.

Researchers in biopharmaceutical, clinical, and academic laboratories use this standard to validate glycan profiling methods, support lot-to-lot comparability studies, and confirm the presence of α2,6 sialylated structures in monoclonal antibodies or glycoproteins. Its rigorous characterization ensures batch-to-batch consistency, making it ideal for QC applications, method development, system suitability assessments, and troubleshooting. This standard pairs effectively with other AdvanceBio N-glycan standards and reagents, allowing comprehensive analysis when combined with exoglycosidase arrays for glycan sequencing. Supplied ready-to-use, it simplifies sample preparation and enhances confidence in glycan identification, quantitation, and structural elucidation across a range of analytical and regulatory workflows.