Agilent, GKIB-005, AdvanceBio InstantAB Human IgG N-glycan Library

AdvanceBio InstantAB Human IgG N-glycan Library. Consists of complex biantennary oligosaccharides consistent with N-glycans on normal human IgG. The reducing termini are derivatized with the fluorescent dye, InstantAB.

Specifications:
Label: InstantAB
Unit: 70 pmol

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The AdvanceBio InstantAB Human IgG N-glycan Library provides researchers with a high-quality, ready-to-use reference set of labeled N-glycans commonly found on human immunoglobulin G. This library enables accurate glycan identification and quantitation in biopharmaceutical characterization, biosimilarity assessment, and glycoprofiling of therapeutic antibodies. Each glycan is expertly labeled with the InstantAB dye, ensuring strong fluorescence signal, improved chromatographic behavior, and compatibility with widely used HPLC and UHPLC platforms.

Designed for streamlined method development and system calibration, this product assists in structure assignment, retention time validation, and supports workflows for intact glycan analysis. It is ideal for use in regulated environments such as quality control or comparability studies, where reliable glycan profiling is essential. The library pairs seamlessly with Agilent’s AdvanceBio Glycan Mapping columns, 1290 Infinity II LC, and 1260 Infinity II LC instruments, as well as associated software solutions for automated glycan analysis. Researchers can use this standard to enhance confidence in glycan assignment and quantitation while supporting robust method validation in antibody-based drug development and production processes. Suitable for both routine and advanced research applications, this library streamlines workflow efficiency and data accuracy in N-glycan analysis.