Agilent, GKIB-101, AdvanceBio InstantAB Man3 / M3 N-glycan Standard

AdvanceBio InstantAB Man3 / M3 N-glycan Standard . N-glycan (conserved trimannosyl core) labeled with InstantAB for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: MAN3

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 1071.3867
Name: Man3
Oxford Name: M3
Standard Type: High Mannose-type Native N-Glycan
Unit: 60 pmol

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This high-quality N-glycan standard is designed for use in glycan analysis workflows to support precise structure assignment and quantitative assessment. It features a well-characterized Man3 M3 N-glycan, derivatized with the AdvanceBio InstantAB label for optimal fluorescence detection and excellent chromatographic performance. Ideal for use as a reference or positive control, this standard enables robust calibration, method development, assay qualification, and system suitability in biopharmaceutical and glycomics research.

Compatible with Agilent HPLC and UHPLC systems, it can be seamlessly integrated into workflows employing the AdvanceBio Glycan Mapping Column and related glycan sample preparation kits. The fluorescent labeling ensures enhanced sensitivity for detection in LC-FLD setups, and it is also amenable to mass spectrometry-based analyses. Researchers involved in monoclonal antibody characterization, biosimilar development, or glycoprotein profiling will benefit from the reliable and reproducible results this standard provides. For extended glycan panel studies, it can be used alongside other AdvanceBio InstantAB labeled glycan standards and mixtures. Each lot is rigorously quality controlled to ensure consistency, making it an essential tool for laboratories prioritizing precision, reproducibility, and regulatory compliance in their glycan analyses.