Agilent, GKIB-106, AdvanceBio InstantAB Man8 / M8 N-glycan Standard

AdvanceBio InstantAB Man8 / M8 N-glycan Standard. N-glycan (oligomannose 8) labeled with InstantAB, for use as a qualitative standard in applications such as liquid chromatography (LC).

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 1881.6507
Name: Man8
Oxford Name: M8
Standard Type: High Mannose-type Native N-Glycan
Unit: 60 pmol

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This analytical standard provides a high-quality, purified Man8 or M8 N-glycan, fluorescently labeled with InstantAB, designed to deliver robust and reliable performance in glycan analysis workflows. It serves as a critical reference for HILIC and other chromatographic methods, enabling confident identification, quantification, and profiling of N-linked glycans in biopharmaceutical development and quality control. This standard ensures reproducibility and comparability across experiments, supporting glycoprofiling of monoclonal antibodies, therapeutic proteins, and other glycosylated biomolecules. It is compatible with Agilent AdvanceBio Glycan Mapping columns and is fully optimized for use with advanced HPLC, UHPLC, and LC-MS systems, including Agilent 1260 Infinity II and 1290 Infinity LC platforms, as well as associated fluorescence detectors. The fluorescence labeling allows for sensitive detection, even at low abundance, making it ideal for routine analysis as well as in-depth structural studies. The standard can be utilized alongside other AdvanceBio glycan standards for method development, instrument calibration, and system suitability testing, facilitating comprehensive coverage and high confidence in glycan identification. It integrates seamlessly into regulated laboratory environments and research settings focused on biotherapeutic characterization and comparability studies.