Agilent, GKIB-305, AdvanceBio InstantAB G2F / FA2G2 N-glycan Standard

AdvanceBio InstantAB G2F / FA2G2 N-glycan Standard. N-glycan (asialo-, galactosylated biantennary, core-substituted with fucose) labeled with InstantAB, for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: F(6)A2G2, NA2F.

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 1947.7090
Name: G2F
Oxford Name: F(6)A2G(4)2
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This N-glycan standard is designed to provide precise and reliable reference material for glycan analysis workflows. It contains highly purified G2F and FA2G2 structures, essential for the accurate identification, quantitation, and characterization of complex N-glycan profiles in biopharmaceutical development and quality control. Predominantly utilized in monoclonal antibody and glycoprotein research, this standard facilitates system suitability testing, calibration, and performance benchmarking in laboratories focused on glycosylation studies.

Optimized for fluorescence-based detection, this product is fully compatible with Agilent’s AdvanceBio InstantAB labeling kits, as well as HPLC and UHPLC systems equipped with fluorescence or mass spectrometry detectors. The standard ensures reproducible retention times and detector responses when used with AdvanceBio Glycan Mapping columns and supports compliance with regulatory requirements for biotherapeutic characterization. Its usage extends to method development, method validation, and troubleshooting analytical procedures in research and regulated environments.

Researchers benefit from high batch-to-batch consistency, enabling confident comparison of analytical data across multiple runs. This standard integrates seamlessly into existing Agilent glycan analysis workflows and is supported by comprehensive technical documentation. It is also suitable for co-use with other industry-standard glycan standards and sample preparation reagents for enhanced application flexibility.