Agilent, GKIB-307, AdvanceBio InstantAB A3 N-glycan Standard

AdvanceBio InstantAB A3 N-glycan Standard. N-glycan (asialo-, agalacto- triantennary complex) labeled with InstantAB, for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: NGA3.

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 1680.6249
Name: A3
Oxford Name: A3
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This N-glycan standard is designed to support accurate and reliable glycan analysis in biopharmaceutical development and quality control. Formulated with InstantAB A3, it provides a ready-to-use mixture of well-characterized N-linked glycans, ideal for use as a reference in chromatographic or mass spectrometric workflows. The standard enables users to confidently characterize glycosylation profiles of therapeutic antibodies and glycoproteins, ensuring comparability and regulatory compliance across projects.

Its application ranges from method development and system suitability testing to routine monitoring of glycan profiles in both research and industrial laboratories. The standard is specifically optimized for high-sensitivity labeling with InstantAB, enabling enhanced detection in liquid chromatography with fluorescence detection and mass spectrometry applications. It is compatible with Agilent AdvanceBio Glycan Mapping columns, InfinityLab LC systems, and a broad range of glycan analysis platforms.

This N-glycan standard streamlines assay preparation by eliminating the need for additional sample processing and supports the validation and harmonization of glycan analysis methods. It serves as a critical tool for analysts seeking consistent data quality and high efficiency in glycoprotein characterization studies. Related products include InstantAB labeling kits, glycan sample preparation reagents, and glycan analysis columns.