Agilent, GKIB-310, AdvanceBio InstantAB G4 / A4G4 N-glycan Standard

AdvanceBio InstantAB G4 / A4G4 N-glycan Standard. N-glycan (asialo-, galactosylated tetraantennary complex N-glycan) labeled with InstantAB, for use as a qualitative standard in applications such as liquid chromatography (LC/HPLC). Alternative glycan name: NA4.

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 2531.9155
Name: G4
Oxford Name: A4G(4)4
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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This N-glycan standard is designed to ensure robust and reliable glycan analysis in biopharmaceutical research and quality control. The included G4 and A4G4 glycan species are highly purified and pre-labeled with InstantAB, facilitating rapid sample preparation and precise quantitation. Researchers can use this standard to validate N-glycan labeling efficiency, optimize separation protocols, and monitor system performance during method development and routine analyses.

It is ideally suited for laboratories conducting structural characterization of therapeutic antibodies, biosimilars, and other glycoproteins, as well as for confirming batch-to-batch consistency and regulatory compliance. The standard is particularly beneficial for users employing high sensitivity techniques such as HPLC, UHPLC, and LC/MS. It provides excellent compatibility with AdvanceBio Glycan Mapping columns and Agilent LC and LC/MS systems, ensuring seamless integration into existing workflows. Additionally, it supports effective method transfer and cross-laboratory harmonization when coupled with other AdvanceBio reagents and consumables. This standard helps researchers save time in method validation and troubleshooting and contributes to obtaining high confidence results in glycosylation profiling.