Agilent, GKIB-311, AdvanceBio InstantAB G2S1 α(2,6) / A2G2S(6)1 N-glycan Standard

AdvanceBio InstantAB G2S1 α(2,6) / A2G2S(6)1 N-glycan Standard . N-glycan (mono-sialylated, galactosylated biantennary complex N-glycan), labeled with InstantAB, for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: A2G2S1, A2G(4)2S(6)1, A1 (α2,6).

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 2092.7465
Name: G2S1 (α2,6)
Oxford Name: A2G(4)2S(6)1
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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The AdvanceBio InstantAB G2S1 α(2,6) / A2G2S(6)1 N-glycan Standard is a high-quality reference material designed to support accurate and reproducible glycan analysis in biopharmaceutical research and quality control. This standard contains a well-characterized biantennary complex N-glycan with a single alpha(2,6)-linked sialic acid, offering a reliable benchmark for method development, system suitability testing, and data calibration.

Ideal for use in analytical workflows such as CE-LIF, HPLC, and LC-MS, the standard facilitates confident identification and quantitation of glycan structures during glycoprotein characterization. It is especially suited for laboratories developing or validating methods for N-glycan profiling of therapeutic proteins, including monoclonal antibodies.

The material is fully compatible with Agilent’s AdvanceBio Glycan Mapping workflows, Glycan Mapping columns, and InstantAB labeling kits, ensuring seamless integration with existing protocols and instruments, including the Agilent 1290 Infinity LC system and 1260 Infinity II Bio-LC. By providing a consistent reference glycan, this standard supports robust performance monitoring and comparative studies, making it a valuable tool for enhancing assay precision and compliance in regulated environments.