Agilent, GKIB-313, AdvanceBio InstantAB G2FS2 α(2,6) / FA2G2S(6)2 N-glycan Standard

AdvanceBio InstantAB G2FS2 α(2,6) / FA2G2S(6)2 N-glycan Standard. N-glycan (di-sialylated, galactosylated biantennary, core-substituted with fucose) labeled with InstantAB, for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: A2F, G2FS2, FA2G2S2, F(6)A2G2S2, F(6)A2G2S(6)2.

Specifications:
Chemical Structure:
Label: InstantAB
Monoisotopic Mass: MWGlycan + 161.05891 = 2529.8998
Name: G2FS2 (α2,6)
Oxford Name: F(6)A2G2S(6)2
Standard Type: Complex-type Native N-Glycan
Unit: 60 pmol

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The AdvanceBio InstantAB G2FS2 α2,6 / FA2G2S6 2 N-glycan Standard is a purified, well-characterized glycan reference standard optimized for precise and reproducible glycan analysis. This standard is specifically designed to aid in the identification and quantitation of complex biantennary, fully sialylated, fucosylated N-glycan structures containing α2,6-linked sialic acids, which are relevant in biopharmaceutical development, quality control, and characterization of therapeutic glycoproteins. Labeled with InstantAB for enhanced fluorescent detection sensitivity, the standard enables streamlined workflows in capillary electrophoresis, ultra-performance liquid chromatography UPLC, and HILIC-based methods. Its compatibility with Agilent’s AdvanceBio Glycan Mapping columns, 1290 Infinity II LC systems, and glycan analysis software ensures optimal performance in both qualitative and quantitative studies. Suited for benchmarking assay performance, validating glycan profiling methods, and serving as a positive control in bioprocess and analytical laboratories, this standard supports regulatory compliance and robust analytical datasets. Ideally incorporated in routine glycoprotein characterization, biosimilar comparability assessments, and QA or QC environments, it ensures confidence and reproducibility in complex glycan analysis workflows across research, development, and manufacturing applications.