Agilent, GKPC-020-P, AdvanceBio InstantPC CHO mAb N-glycan library plus CHO mAb glycoprotein (formerly ProZyme)

AdvanceBio InstantPC CHO mAb N-glycan library plus CHO mAb glycoprotein (formerly ProZyme). Library consists of complex biantennary and high mannose N-glycans present in many CHO derived monoclonal antibodies (mAbs). The reducing termini are derivatized with the fluorescent dye, InstantPC. GKPC-020-P also includes 0.25 mg of the CHO mAb glycoprotein from which this library was derived

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The AdvanceBio InstantPC CHO mAb N-glycan library plus CHO mAb glycoprotein is a highly curated reference set designed to advance the characterization and quantitation of N-glycans from Chinese Hamster Ovary monoclonal antibodies. The set includes both a comprehensive library of pre-labeled, purified N-glycans and a well-characterized glycoprotein standard, providing an essential tool for method development, system suitability, and data validation in biopharmaceutical development. Optimized for streamlined workflows, it supports glycan analysis via UHPLC, LC-MS, and CE using InstantPC labeling chemistry, ensuring sensitive detection and reliable reproducibility. Commonly used in quality control, comparability studies, and batch release testing, this library accelerates rapid glycan profiling critical for biosimilar development and product consistency assessment. It is fully compatible with Agilent AdvanceBio Glycan Mapping columns and the Agilent 1290 Infinity II LC system as well as other major platforms for glycan analysis. This product facilitates confident structure assignment and quantification, supporting compliance with regulatory expectations in therapeutic antibody research and manufacturing. Backed by extensive characterization, this library supports robust, reproducible workflows for comprehensive N-glycan analysis in diverse research and industrial environments.