Agilent, GKPC-302, AdvanceBio InstantPC G0F / FA2 N-glycan standard

AdvanceBio InstantPC G0F / FA2 N-glycan standard . N-glycan (asialo-, agalacto-, biantennary complex N-glycan, core-substituted with fucose) labeled with InstantPC, for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: F(6)A2, NGA2F.

Specifications:
Chemical Structure:
Label: InstantPC
Monoisotopic Mass: MWGlycan + 261.14773 = 1723.6922
Name: G0F
Oxford Name: F(6)A2
Standard Type: Complex-type Native N-Glycan
Unit: 25 Injections

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This N-glycan standard provides a precise quantification and identification tool for released N-glycans, specifically the G0F (FA2) glycoform. Labeled with InstantPC, the standard offers enhanced sensitivity and fluorescence for streamlined detection using LC-FLD or LC-MS platforms. Ideally suited for biopharmaceutical researchers, it serves as a critical reference in glycan profiling, method validation, and system suitability assessment.

The standard supports robust characterization of monoclonal antibodies, biosimilars, and other glycoproteins, ensuring accuracy for quality control and regulatory compliance studies. Its high purity and reproducibility facilitate comparison across experiments and laboratories. Designed for compatibility with Agilent AdvanceBio Glycan Mapping workflows, it works seamlessly with Agilent InfinityLab LC systems, 1290 Infinity II LC, 1260 Infinity II LC, and associated fluorescence or mass spectrometry detectors.

In addition, this standard can be used alongside other AdvanceBio InstantPC glycan standards or kits to construct calibration curves, validate peak assignment, or monitor instrument performance. Its ready-to-use format reduces sample preparation time, supporting high-throughput environments. As part of a comprehensive glycan analysis solution, this N-glycan standard streamlines the workflow for pharmaceutical development, lot release, and in-process monitoring applications.