Agilent, GKPC-318, AdvanceBio InstantPC G2FGa2 / FA2G2Ga(3)2 N-glycan standard

AdvanceBio InstantPC G2FGa2 / FA2G2Ga(3)2 N-glycan standard. N-glycan (asialo-, di-galactosylated, biantennary complex N-glycan, core-subsituted with fucose and with 2 α(1,3) galactose) labeled with InstantPC, for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative Glycan names: G2F with 2 alpha gal, F(6)A2G(4)2Ga2, NA2Ga2F.

Specifications:
Chemical Structure:
Label: InstantPC
Monoisotopic Mass: MWGlycan + 261.14773 = 2371.9034
Name: G2FGa2
Oxford Name: F(6)A2G(4)2Ga(3)2
Standard Type: Complex-type Native N-Glycan
Unit: 25 Injections

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This highly purified N-glycan standard features G2FGa2 and FA2G2Ga(3)2 structures, derivatized with InstantPC to enhance fluorescence and mass spectrometry sensitivity. Optimized for glycan analysis workflows, it facilitates accurate retention time alignment, qualitative identification, and quantitation of complex glycan species in biopharmaceutical and academic research settings. The standard is ideally suited for method development, system suitability testing, and instrument calibration in high-throughput glycomics and quality control laboratories.

Engineered for optimal compatibility, the standard is validated for use with Agilent AdvanceBio Glycan Mapping columns, UHPLC and HPLC systems, and Agilent Q-TOF and triple quadrupole LC-MS platforms. It integrates seamlessly with automated sample preparation solutions and Agilent MassHunter and OpenLab software for comprehensive data analysis. Additionally, the standard is a critical tool when evaluating sample preparation kits and fluorescence detection systems.

Incorporating this well-characterized reference into analytical workflows ensures robust performance monitoring and reliable data for applications such as characterization of therapeutic antibodies and glycoproteins. It also supports validation of glycan profiling methods, inter-laboratory comparisons, and training of analytical personnel in the biopharmaceutical industry or academic research environments.