Agilent, GKSA-102, AdvanceBio 2-AA Man3F / FM3 N-glycan standard (formerly ProZyme).

AdvanceBio 2-AA Man3F / FM3 N-glycan standard (formerly ProZyme). N-glycan (conserved trimannosyl core substituted with fucose) labeled with 2-aminobenzoic acid (2-AA), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: M3N2F, F(6)M3.

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 120.06875 = 1176.4544
Name: Man3F
Oxford Name: F(6)M3
Standard Type: Native N-Glycan Core
Unit: 100 pmol

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The AdvanceBio 2-AA Man3F / FM3 N-glycan standard is a high-quality reference glycan designed for reliable and accurate N-glycan analysis in biopharmaceutical development and glycomics research. Labeled with 2-aminobenzoic acid (2-AA), this standard enables sensitive fluorescence detection and precise quantitation when used in HPLC, UHPLC, or LC-MS workflows. It is ideal for confirming the presence, retention time, and structure of the Man3F glycan, which is commonly found in therapeutic antibodies and glycoproteins. This standard supports method development, system suitability testing, and quality control in the analysis of released N-glycans. Laboratories conducting biosimilar characterization, vaccine research, and glycoprotein profiling benefit from its well-defined structure and reproducibility. It is fully compatible with Agilent AdvanceBio Glycan Mapping columns and systems, such as the InfinityLab LC Series and 1260 Infinity II Bio-inert LC, as well as other mainstream HPLC and MS platforms. For comprehensive data analysis, it is suited for use with Agilent MassHunter and OpenLab software. This standard streamlines workflow setup and data validation, ensuring robust and consistent glycan characterization across a variety of research and quality assurance applications.