Agilent, GKSA-103, AdvanceBio 2-AA Man5 / M5 N-glycan standard (formerly ProZyme)

AdvanceBio 2-AA Man5 / M5 N-glycan standard (formerly ProZyme). N-glycan (oligomannose 5) labeled with 2-aminobenzoic acid, (2-AA), also known as anthranilic acid, for use as a qualitative standard in applications such as liquid chromatography (LC).

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 121.05276 = 1355.4861
Name: Man5
Oxford Name: M5
Standard Type: High Mannose-type Native N-Glycan
Unit: 100 pmol

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The AdvanceBio 2-AA Man5 / M5 N-glycan standard is a high-purity, 2-aminobenzoic acid labeled Man5 (M5) N-glycan reference material designed to support accurate and reliable glycan analysis. This standard is intended for use in the identification, quantitation, and profiling of N-linked glycans in biopharmaceutical development, quality control, and glycomics research. Its well-characterized structure ensures consistent performance when validating glycan analytical workflows, facilitating method development, system suitability testing, and inter-laboratory comparisons.

Optimized for compatibility with liquid chromatography and mass spectrometry platforms, including Agilent AdvanceBio Glycan Mapping columns and LC-MS systems, it enables precise elution time and peak identification. It is also suitable for use with fluorescence and UV detectors, ensuring flexibility across a wide range of analytical techniques. Researchers performing monoclonal antibody characterization, biosimilar comparability, and glycoprotein quality assessment will benefit from its robust and reproducible results. As part of the comprehensive AdvanceBio N-glycan standard portfolio, this product complements other glycan standards and labeling kits to streamline workflows and assure high accuracy in glycan profiling studies.