Agilent, GKSA-307, AdvanceBio 2-AA A3 N-glycan Standard

AdvanceBio 2-AA A3 N-glycan Standard. N-glycan (asialo-, agalacto- triantennary) labeled with 2-aminobenzoic acid (2-AA, also known as anthranilic acid), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan name: NGA3

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 121.05276 = 1640.6187
Name: A3
Oxford Name: A3
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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The AdvanceBio 2-AA A3 N-glycan Standard is a high-purity, well-characterized reference specifically designed for glycan analysis workflows in biopharmaceutical and academic laboratories. This standard contains 2-aminobenzoic acid (2-AA) labeled A3 N-glycan, providing consistent and reliable peak identification for method development, system suitability testing, and quality assurance in glycosylation profiling. It serves as a critical control in the characterization of monoclonal antibodies, glycoproteins, and other biologics, enhancing accuracy in both qualitative and quantitative analyses.

Ideally suited for use in high-performance liquid chromatography HPLC and ultra high-performance liquid chromatography UHPLC systems, this standard supports a variety of detection techniques, including fluorescence and mass spectrometry MS. It is especially compatible with Agilent AdvanceBio Glycan Mapping Columns and integrates seamlessly with Agilent LC and LCMS platforms, such as the 1290 Infinity II and 6545XT AdvanceBio LCMS systems. Used in conjunction with Agilent’s comprehensive portfolio of glycan labeling kits and sample preparation solutions, the standard facilitates robust method validation and routine monitoring. Its verified lot-to-lot consistency and traceability support regulatory compliance and reproducibility in glycan research, delivering confidence in critical glycan analysis applications.