Agilent, GKSA-308, AdvanceBio 2-AA A3G3 N-glycan Standard

AdvanceBio 2-AA A3G3 N-glycan Standard. N-glycan (asialo-, galactosylated triantennary) labeled with 2-aminobenzoic acid (2-AA, also known as anthranilic acid), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: A3G(4)3, NA3.

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 121.05276 = 2126.7771
Name: G3
Oxford Name: A3G(4)3
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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This N-glycan standard is a highly purified reference material designed for the accurate identification and quantification of complex N-glycans in biopharmaceutical and glycomics research. Comprising the well-characterized A3G3 glycan structure, it is pre-labeled with 2-aminobenzoic acid (2-AA) to enable sensitive fluorescence and mass spectrometric detection. The product streamlines workflow standardization and supports robust method development, system qualification, and glycan mapping of therapeutic antibodies, glycoproteins, and vaccine candidates. It is ideal for laboratories engaged in QC testing and comparability studies, facilitating reliable assessment of glycosylation profiles in accordance with regulatory guidance. Optimal results are achieved with Agilent AdvanceBio Glycan Mapping columns and the InfinityLab LC Series or comparable UHPLC systems. The standard is supplied as a ready-to-use solution requiring minimal preparation, thereby enhancing reproducibility and reducing setup time. Its precise composition allows for effective calibration and quantitation when analyzing unknown samples, supporting data integrity across analytical platforms. This product is also compatible with Agilent MassHunter or OpenLab software suites for streamlined data analysis and glycan identification. Overall, it provides an essential control for increased confidence in glycan analysis workflows.