Agilent, GKSA-309, AdvanceBio 2-AA A4 N-glycan Standard

AdvanceBio 2-AA A4 N-glycan Standard. N-glycan (asialo-, agalacto-, tetraantennary) labeled with 2-aminobenzoic acid (2-AA, also known as anthranilic acid), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan name: NGA4.

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 121.05276 = 1843.6981
Name: A4
Oxford Name: A4
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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AdvanceBio 2-AA A4 N-glycan Standard is a high-quality reference material designed to support accurate and robust N-glycan analysis. This purified standard contains a well-characterized, 2-aminobenzoic acid labeled, biantennary complex-type glycan, enabling precise method development, system suitability testing, and calibration in glycomics workflows. It facilitates reliable quantitation and comparison of sample glycans in biopharmaceutical research and quality control.

Ideal for laboratories involved in monoclonal antibody characterization or therapeutic glycoprotein profiling, this standard is optimized for use in hydrophilic interaction liquid chromatography (HILIC), UHPLC, and LC fluorescence detection workflows. It seamlessly integrates with Agilent AdvanceBio Glycan Mapping columns and is fully compatible with Agilent HPLC, 1260 Infinity II, and 1290 Infinity II LC systems. Researchers can also employ this standard in combination with Agilent’s 2-AA labeling kits for comprehensive N-glycan analysis.

With consistent lot-to-lot reproducibility and robust performance, it ensures confidence in data quality for routine or advanced glycan characterization. This product streamlines method validation, instrument performance checks, and routine monitoring of sample preparation efficiency, supporting compliance in regulated laboratory environments.