Agilent, GKSA-310, AdvanceBio 2-AA G4 / A4G4 N-glycan standard (formerly ProZyme)

AdvanceBio 2-AA G4 / A4G4 N-glycan standard (formerly ProZyme). N-glycan (asialo-, galactosylated tetraantennary complex N-glycan) labeled with 2-aminobenzoic acid (2-AA), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan name: A4G(4)4, NA4.

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 120.06875 = 2490.9253
Name: G4
Oxford Name: A4G(4)4
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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The AdvanceBio 2-AA G4 A4G4 N-glycan standard is a high-purity reference material designed for accurate glycan analysis in biopharmaceutical and clinical research. Labeled with 2-aminobenzoic acid, this standard provides well-characterized G4 and A4G4 N-glycan structures suitable for calibration and system suitability testing. It is ideal for analysts performing structural characterization and quantitation of glycans using chromatographic or mass spectrometric methods. Typical applications include quality control of monoclonal antibodies, analysis of glycoproteins, biosimilar comparability, and glycoengineering studies. The standard supports method validation, analytical development, and assay reproducibility by enabling precise retention time alignment and facilitating peak identification. Optimized for use with Agilent’s AdvanceBio Glycan Mapping columns and compatible with high-performance liquid chromatography and liquid chromatography-mass spectrometry workflows, it integrates seamlessly into glycan profiling protocols. This product enhances data confidence when combined with Agilent’s sample preparation kits and analytical instruments such as InfinityLab LC systems and 6545XT AdvanceBio LC/Q-TOF. The AdvanceBio 2-AA G4 A4G4 N-glycan standard is a critical tool for laboratories seeking reliable, reproducible results in advanced glycomics research and pharmaceutical development.