Agilent, GKSA-313, AdvanceBio 2-AA G2FS2 α(2,6) / FA2G2S(6)2 N-glycan standard (formerly ProZyme)

AdvanceBio 2-AA G2FS2 α(2,6) / FA2G2S(6)2 N-glycan standard (formerly ProZyme). N-glycan (di-sialylated-, galactosylated biantennary, core-substituted with fucose labeled with 2-aminobenzoic acid (2-AA), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: G2FS2, FA2G2S2, F(6)A2G2S2, F(6)A2G2S(6)2, A2F

Specifications:
Chemical Structure:
Label: 2-AA
Monoisotopic Mass: MWGlycan + 120.06875 = 2488.9096
Name: G2FS2 (α2,6)
Oxford Name: F(6)A2G2S(6)2
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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This high-quality N-glycan standard features 2-AA labeled G2FS2 α(2,6) and FA2G2S(6)2 structures, ideal for robust analytical workflows in glycan profiling. The standard supports precise performance verification, calibration, and system suitability testing across a range of research applications including biologics characterization, quality control in therapeutic glycoprotein development, and biopharmaceutical comparability studies. Optimized for use with Agilent’s AdvanceBio Glycan Mapping and HILIC columns, it seamlessly integrates with high-sensitivity liquid chromatography and mass spectrometry platforms, such as the Agilent 1290 Infinity II LC and 6545XT AdvanceBio LC/Q-TOF. Supplied in a format consistent with previous ProZyme formulations, it enables transferability and comparability for established protocols. Users benefit from enhanced reproducibility in glycan identification and quantitation due to the standard’s stringent manufacturing controls and characterization. This product is also suitable for benchmarking new methods and training analyses, improving laboratory confidence in glycomics workflows. Compatible with related Agilent kits for sample preparation and labeling, it provides a reliable reference to streamline regulatory compliance and accelerate critical method validation. Designed for advanced research in biopharma, academia, and clinical development, this N-glycan standard is an essential component of comprehensive glycan analysis strategies.