Agilent, GKSB-002, AdvanceBio 2-AB Bovine Fetuin N-glycan Library

AdvanceBio 2-AB Bovine Fetuin N-glycan Library. Composed of a mixture of sialylated N-linked glycans (core non-fucosylated), consistent with N-glycans previously reported for bovine fetuin. The biantennary glycans can have one or two of the sialic acid residues (NeuAc). The triantennary glycans can have from one to four of the sialic acid residues. The sialic acid residues are found in both α(2,3) and α(2,6) linkages. Triantennary glycans constitute ~85% of total glycans present. A small amount of penta-sialylated glycans can be detected, but their structure has not been determined. The reducing termini are derivatized with the fluorescent dye, 2-AB.

Specifications:
Label: 2-AB
Unit: 200 pmol

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The AdvanceBio 2-AB Bovine Fetuin N-glycan Library provides a robust reference standard for reliable characterization and identification of N-glycans in glycoprotein research. This well-defined library contains 2-aminobenzamide (2-AB) labeled N-glycans released from bovine fetuin, offering a comprehensive representation of complex, sialylated N-glycan structures. Researchers can use this library to evaluate and optimize glycan analysis workflows, validate glycan identification algorithms, and support process development or quality control in biopharmaceutical analysis.

Optimized for compatibility with Agilent AdvanceBio Glycan Mapping columns and Agilent HPLC, UHPLC, and LC-MS platforms, this library delivers high sensitivity and reproducibility in both qualitative and quantitative studies. It is an essential tool for laboratories engaged in monoclonal antibody characterization, biosimilar development, and glycoprotein profiling. When combined with Agilent’s complete glycan analysis solutions and related consumables, this N-glycan standard enhances the accuracy of retention time mapping, system suitability assessments, and method validation.

Ready-to-use and quality controlled, this product ensures confidence in your glycomics workflows. Its broad applicability supports both routine and advanced research, making it an indispensable resource for analytical scientists and researchers focusing on glycan structure elucidation and biomolecule characterizations.