Agilent, GKSB-005, AdvanceBio 2-AB Human IgG N-glycan Library

AdvanceBio 2-AB Human IgG N-glycan Library. Consists of complex biantennary oligosaccharides consistent with N-glycans on normal human IgG. The reducing termini are derivatized with the fluorescent dye, 2-AB (2-aminobenzamide).

Specifications:
Label: 2-AB
Unit: 200 pmol

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The AdvanceBio 2-AB Human IgG N-glycan Library provides a high-quality standard for comprehensive glycan analysis in biopharmaceutical research and quality control. This library contains a range of well-characterized, 2-aminobenzamide labeled N-linked glycans derived from human immunoglobulin G, offering researchers a robust reference for N-glycan profiling. It is ideally suited for method development, system suitability testing, and accurate peak identification in the characterization of therapeutic antibodies and related products.

The product is designed for use with liquid chromatography methods, particularly HILIC and reverse-phase LC, and is fully compatible with leading analytical platforms such as Agilent HPLC, UHPLC, and LC-MS systems. Use in conjunction with Agilent’s AdvanceBio Glycan Mapping columns and related glycan labeling kits is recommended for optimal performance. This library supports efficient identification and quantitation of major IgG N-glycan species, aiding in regulatory submissions and process monitoring during bioprocess development.

With its traceable composition and batch-to-batch consistency, it ensures reliable results in released N-glycan analysis, facilitating compliance with analytical standards required in the biopharmaceutical industry. It is an essential tool for laboratories focused on glycoprofiling of therapeutic antibodies.