Agilent, GKSB-102, AdvanceBio 2-AB Man3F / FM3 N-glycan Standard

AdvanceBio 2-AB Man3F / FM3 N-glycan Standard. N-glycan (conserved trimannosyl core substituted with fucose) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: M3N2F, F(6)M3.

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan  + 120.06875 = 1176.4544
Name: Man3F
Oxford Name: F(6)M3
Standard Type: Native N-Glycan Core
Unit: 100 pmol

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This high-quality N-glycan standard offers a precisely characterized 2-aminobenzamide labeled Man3F and FM3 mixture, ideal for robust glycan analysis workflows. Specifically engineered for method development, system suitability assessment, and as a quantitation reference, this standard enables confident identification and quantification of core fucosylated and high mannose glycan species. It is designed for seamless compatibility with fluorescence or mass spectrometry detection platforms and integrates smoothly into routine and advanced workflows for biopharmaceutical characterization, glycoprotein QC, and detailed structural analysis.

Researchers in the field of biotherapeutic development, biosimilar evaluation, and academic glycosciences will benefit from its ability to ensure traceable, reproducible results when assessing glycan profiles. The standard is perfectly suited for use with Agilent AdvanceBio Glycan Mapping columns and Agilent LC and LC-MS systems, while also performing accurately with alternative HPLC and UHPLC setups. For comprehensive glycan characterization, it complements additional AdvanceBio N-glycan standards and a full suite of glycan sample preparation reagents. This reliable reference is an optimal choice to support regulatory submissions, method validation studies, and routine monitoring of critical glycosylation attributes in complex biological samples.