Agilent, GKSB-103, AdvanceBio 2-AB Man5 / M5 N-glycan Standard

AdvanceBio 2-AB Man5 / M5 N-glycan Standard. N-glycan (oligomannose 5) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC).

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan + 120.06875 = 1354.5021
Name: Man5
Oxford Name: M5
Standard Type: High Mannose-type Native N-Glycan
Unit: 100 pmol

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This N-glycan standard offers a highly purified 2-aminobenzamide labeled Man5 (M5) structure, commonly found in biopharmaceutical glycoproteins and monoclonal antibodies. Designed for method development, system suitability testing, and quantitative analysis, it enables accurate benchmarking of sample preparation, labeling, and chromatographic workflows. This standard is optimized for use with Agilent AdvanceBio Glycan Mapping workflows and is compatible with HILIC-UPLC or UHPLC analysis, ensuring robust and reproducible glycan profiling. Researchers in biotherapeutic characterization, process development, and quality control can employ this standard for ensuring peak assignment confidence and monitoring analytical system performance. It serves as an essential positive control for quantitative and qualitative N-glycan analysis in regulated and non-regulated laboratory settings. The 2-AB label provides strong fluorescence, facilitating detection using common HPLC and UPLC systems equipped with fluorescence or MS detectors. This product aligns with a range of Agilent sample preparation consumables, columns, and analytical platforms, supporting integrated glycan analysis solutions. Ideal for laboratories working on biosimilar development, glycosylation profiling, and quality assurance, this standard ensures analytical reliability and data comparability across multiple glycomic studies.