Agilent, GKSB-105, AdvanceBio 2-AB Man7 / M7 N-glycan Standard

AdvanceBio 2-AB Man7 / M7 N-glycan Standard. N-glycan (oligomannose 7) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC).

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan + 120.06875 = 1678.6077
Name: Man7
Oxford Name: M7
Standard Type: High Mannose-type Native N-Glycan
Unit: 100 pmol

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This N-glycan standard is a highly purified, 2-aminobenzamide labeled mannosylated heptasaccharide (Man7, M7), designed for use in glycan analysis workflows. As an essential reference material, it supports accurate identification, profiling, and quantitation of N-linked glycans in monoclonal antibodies and glycoproteins. The standard is produced under stringent quality controls to ensure batch-to-batch consistency, making it ideal for laboratories conducting method development, system suitability testing, or maintaining regulatory compliance in biopharmaceutical research.

The 2-AB fluorescent labeling allows sensitive detection using high performance liquid chromatography with fluorescence detection or mass spectrometric analysis. It is fully compatible with the Agilent AdvanceBio Glycan Mapping workflow, including LC systems such as the 1260 and 1290 Infinity II series as well as Agilent MassHunter software. This product also integrates seamlessly with other exoglycosidase arrays and glycan labeling kits available from the same portfolio, optimizing analytical performance in complex sample matrices. Recommended usage scenarios include glycosylation pattern characterization, quality control of therapeutic proteins, and process development. Overall, this standard provides robust support for reproducible and precise glycan analytics in diverse life science and pharmaceutical research environments.