Agilent, GKSB-106, AdvanceBio 2-AB Man8 / M8 N-glycan Standard

AdvanceBio 2-AB Man8 / M8 N-glycan Standard. N-glycan (oligomannose 8) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: Man8, M8.

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan + 120.06875 = 1840.6605
Name: Man8
Oxford Name: M8
Standard Type: High Mannose-type Native N-Glycan
Unit: 100 pmol

**********The following product description is generated by AI and is for reference only. If you have any questions, please contact customer service.**********
This high-purity N-glycan standard, labeled with 2-aminobenzamide (2-AB), provides a reliable reference for accurate characterization and quantitation of high-mannose Man8 glycans in biopharmaceutical research. Designed for use in the analysis of monoclonal antibodies, therapeutic proteins, and other glycoproteins, the standard supports method development, system suitability testing, and routine release or comparability studies.

Ideally suited for HPLC, UHPLC, and LC-MS workflows, the standard serves as a benchmark in glycan profiling and identification, ensuring confidence in glycosylation monitoring and process consistency. Its consistent labeling and rigorous quality control enable sensitivity and reproducibility during fluorescence detection or mass spectrometry analysis.

Compatible with Agilent AdvanceBio Glycan Mapping columns and sample preparation kits, the standard can be seamlessly integrated into established Agilent workflows. It is also suitable for use with comparable platforms and analytical systems, aiding laboratories focused on regulatory compliance, product characterization, and biosimilar development.

Researchers benefit from the accurate retention and migration time provided by this standard, supporting critical decisions in glycoform analysis. The product is supplied ready to use and meets stringent requirements for reproducibility, facilitating reliable inter-laboratory comparisons and system performance verification.