Agilent, GKSB-303, AdvanceBio 2-AB G0FB / FA2B N-glycan Standard

AdvanceBio 2-AB G0FB / FA2B N-glycan Standard. N-glycan (asialo-, agalacto-, biantennary complex N-glycan, core-substituted with fucose and with bisecting GlcNAc) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: F(6)A2B, NGA2FB.

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan + 120.06875 = 1785.6926
Name: G0FB
Oxford Name: F(6)A2B
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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This certified N-glycan standard enables precise identification and quantitation of G0FB and FA2B N-glycan structures in biopharmaceutical and glycoprotein research. Each vial is pre-labeled with 2-aminobenzamide (2-AB), ensuring robust fluorescence detection in LC or UHPLC workflows. Ideal for verifying glycan assignments, system suitability testing, and method development, the standard provides consistent, reproducible results for laboratories focused on glycoprofile analysis of monoclonal antibodies, therapeutic proteins, and serum samples.

Researchers can confidently use this standard for identification confirmation or as a retention time calibrant in hydrophilic interaction liquid chromatography HILIC separations. It is fully compatible with Agilent AdvanceBio Glycan Mapping columns, Agilent HPLC and UHPLC systems, and integrates seamlessly with leading glycan analysis software. The standard complements a range of 2-AB labeled glycan libraries, supporting both release-to-report workflows and detailed structural elucidation in regulated environments.

This product streamlines analytical validation, allows reliable method performance checks, and enhances data traceability, making it an essential component in high-quality glycomics laboratories engaged in product characterization, quality control, and process development.