Agilent, GKSB-304, AdvanceBio 2-AB G2 / A2G2 N-glycan Standard

AdvanceBio 2-AB G2 / A2G2 N-glycan Standard . N-glycan (asialo-, galactosylated biantennary) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: A2G(4)2, NA2.

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan + 120.06875 = 1760.6609
Name: G2
Oxford Name: A2G(4)2
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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The AdvanceBio 2-AB G2 / A2G2 N-glycan Standard is a high-quality reference material designed for precise glycan analysis in biopharmaceutical research and development. This product features well-characterized N-glycan structures, labeled with 2-aminobenzamide (2-AB), enabling sensitive and accurate detection via HPLC, UHPLC, and LC-MS systems. Widely used for method development, system qualification, and routine performance monitoring, it supports robust analysis of glycosylation profiles in monoclonal antibodies, therapeutic proteins, and biosimilars. Its defined composition ensures reproducibility and consistency, making it ideal for laboratories seeking validation or calibration standards during glycan characterization workflows. The standard is fully compatible with Agilent’s AdvanceBio Glycan Mapping workflow, including AdvanceBio Glycan Mapping columns and 2-AB labeling kits, and can be integrated with a range of analytical instruments such as Agilent 1260 Infinity II and 1290 Infinity LC systems. Researchers engaged in quality control, clone selection, or comparability studies will benefit from the confidence this standard provides in quantitative and qualitative glycan analyses. Comprehensive documentation and lot-to-lot consistency further support compliance with regulatory requirements in biopharma settings.