Agilent, GKSB-315, AdvanceBio 2-AB G2FS1 α(2,6) / FA2G2S(6)1 N-glycan Standard

AdvanceBio 2-AB G2FS1 α(2,6) / FA2G2S(6)1 N-glycan Standard. N-glycan (mono-sialylated-, galactosylated biantennary N-glycan, core-substituted with fucose) labeled with 2-aminobenzamide (2-AB), for use as a qualitative standard in applications such as liquid chromatography (LC). Alternative glycan names: A1F, FA2G2S1, F(6)A2G2S1, F(6)A2G(4)2S(6)1, A1F.

Specifications:
Chemical Structure:
Label: 2-AB
Monoisotopic Mass: MWGlycan + 120.06875 = 2197.8142
Name: G2FS1 (α2,6)
Oxford Name: F(6)A2G(4)2S(6)1
Standard Type: Complex-type Native N-Glycan
Unit: 100 pmol

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The AdvanceBio 2-AB G2FS1 α(2,6) / FA2G2S(6)1 N-glycan Standard is a highly characterized glycan reference material designed for robust and precise glycosylation analysis. Featuring 2-aminobenzamide (2-AB) labeled N-glycans, this standard is ideal for system calibration, method validation, and accurate identification of complex glycan structures during biopharmaceutical development and quality control. It supports workflows in released N-glycan profiling, allowing researchers to determine glycosylation patterns for therapeutic antibodies, fusion proteins, and other glycoproteins.

Common applications include monitoring lot-to-lot consistency, confirming glycan identity, and benchmarking chromatographic or mass spectrometry systems. It is optimized for use with ultra-high-performance liquid chromatography UPLC, high-performance liquid chromatography HPLC, and compatible with Agilent AdvanceBio Glycan Mapping columns and Agilent LC fluorescence detection systems. This standard aids in achieving confident structural elucidation and quantitation by offering consistent retention times and robust signal response. Ideal for use in regulated or research environments, it complements a wide range of Agilent glycan analysis reagents and workflows, ensuring reliable and reproducible analytical results in N-glycan characterization.