Agilent, GKSB-503, AdvanceBio 2-AB Glucose Homopolymer Standard

AdvanceBio 2-AB Glucose Homopolymer Standard. Consists of a mixture of α(1-6)-linked glucose oligosaccharides with variable number of monomeric glucose units (1-23 or more). The reducing termini are derivatized with 2-AB (2-aminobenzamide). May be used as a ladder standard for HILIC separations of 2-AB labeled N-glycans, and can aid in the calculation of glucose unit (GU) values.

Specifications:
Label: 2-AB
Unit: 200 pmol

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The AdvanceBio 2-AB Glucose Homopolymer Standard is a high-quality reference material designed for accurate and reliable characterization of glycan profiles in biopharmaceutical research. This standard is ideal for laboratories engaged in the analysis of glycosylation patterns, supporting quality control, process development, and comparability studies for therapeutic proteins and monoclonal antibodies. Labeled with 2-aminobenzamide (2-AB), the homopolymer enables sensitive fluorescent detection, delivering robust performance in various analytical workflows.

Researchers can use this standard to calibrate and validate liquid chromatography systems, ensuring reproducible retention times and precise quantitation of glycan species. It is particularly useful in high-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UHPLC) methods, and is fully compatible with Agilent’s AdvanceBio Glycan Mapping columns and associated sample preparation kits. Its defined composition assists in benchmarking system performance and optimizing glycan separation conditions.

This standard supports seamless integration into regulated environments and is suitable for use with a wide range of fluorescence detection instruments and software platforms. By providing consistent peak identification and quantification, it streamlines method development and troubleshooting, enhancing confidence in glycan analysis results throughout research and quality assurance workflows.