Agilent, GKSP-005, AdvanceBio APTS Human IgG N-glycan Library

AdvanceBio APTS Human IgG N-glycan Library. Consists of complex biantennary oligosaccharides consistent with N-glycans on normal human IgG. The reducing termini are derivatized with the fluorescent dye, 8-aminopyrene-1,3,6-trisulfonic acid trisodium salt (APTS) for separation by capillary electrophoresis (CE).

Specifications:
Label: APTS
Unit: 120 pmol

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This comprehensive library offers a high-quality collection of fluorescently labeled human IgG N-glycans prepared using the APTS labeling technique, ensuring optimal separation and identification. Designed to streamline glycan analysis, the set is ideal for the qualitative and quantitative profiling of N-linked glycosylation patterns in monoclonal antibodies and other therapeutic proteins. Each glycan standard is meticulously characterized, providing researchers with reliable retention time and migration data for method development, system suitability testing, and data validation.

The library is particularly suited for use with capillary electrophoresis systems, including Agilent’s CE instruments and the Agilent 1290 Infinity II LC system when equipped with fluorescence detection. Analytical laboratories engaged in biopharmaceutical development or biosimilar characterization will benefit from the consistency and versatility of this ready-to-use kit. The resource aligns seamlessly with AdvanceBio Glycan Mapping workflows and is compatible with dedicated Agilent AdvanceBio Glycan columns and associated software solutions for enhanced data integration and analysis. Utilization of this glycan library helps ensure regulatory compliance and method transferability in quality control and research environments focused on therapeutic antibody glycosylation.