Agilent, GKSP-103, AdvanceBio APTS Man5 / M5 N-glycan Standard

AdvanceBio APTS Man5 / M5 N-glycan Standard. N-glycan (oligomannose 5) labeled with 8-aminopyrene-1,3,6-trisulfonate (APTS), for use as a qualitative standard in applications such as capillary electrophoresis (CE).

Specifications:
Chemical Structure:
Label: APTS
Monoisotopic Mass: MWGlycan + 440.9647 = 1675.3981
Name: Man5
Oxford Name: M5
Standard Type: High Mannose-type Native N-Glycan
Unit: 60 pmol

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This N-glycan standard provides a highly purified, well-characterized Man5 (M5) oligosaccharide conjugated with 2-aminopyridine (APTS), optimized for advanced glycan analysis workflows. Designed for exceptional reliability, it serves as a critical reference material for qualitative and quantitative studies in biopharmaceutical development, quality control, and glycosylation profiling. The standard supports robust method development and system suitability testing in applications such as therapeutic monoclonal antibody and glycoprotein characterization.

Intended for use with capillary electrophoresis, liquid chromatography, and high-resolution mass spectrometry platforms, the standard is fully compatible with Agilent AdvanceBio Glycan Mapping workflows, including the Agilent 1290 Infinity II LC and Agilent 6200 Series TOF or 6545XT AdvanceBio LC-QTOF systems. Researchers benefit from its precise retention time and migration profile, supporting accurate identification and quantification in complex biological samples. This standard is aligned with commonly encountered N-glycan structures in therapeutic proteins, enabling effective comparison and validation of glycoanalytical protocols.

Paired seamlessly with additional AdvanceBio glycan standards, columns, and labeling kits, this product facilitates comprehensive and reproducible glycan analysis in regulated and discovery environments. It is supplied with a certificate of analysis, ensuring confidence in traceability and performance for critical research and routine testing needs.