Agilent, GKSP-233, AdvanceBio APTS α(2,3) Sialylated triantennary N-glycan Library

AdvanceBio APTS α(2,3) Sialylated triantennary N-glycan Library. Library consists of triantennary oligosaccharides containing α(2,3) linked sialic acid. The reducing termini are derivatized with the fluorescent dye, 8-aminopyrene-1,3,6-trisulfonate (APTS), for separation by capillary electrophoresis (CE).

Specifications:
Label: APTS
Unit: 120 pmol

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This highly characterized APTS-labeled alpha(2,3) sialylated triantennary N-glycan reference standard is designed for advanced glycan analysis workflows. The library features a purified, structurally well-defined glycan, enabling reliable retention time assignment and positive identification of triantennary N-glycans with alpha(2,3) sialylation in biopharmaceutical characterization, quality control, and method development. Conjugation with 8-aminopyrene-1,3,6-trisulfonic acid (APTS) ensures strong fluorescence signal and compatibility with high-sensitivity detection methods.

Optimized for use in conjunction with capillary electrophoresis-LIF (CE-LIF) platforms such as the Agilent CE and Fragment Analyzer systems, this glycan standard also supports workflows involving UPLC, HPLC, and mass spectrometry. Its application extends to glycoprofiling of therapeutic antibodies, vaccine candidates, and protein-based drugs, assisting in monitoring lot-to-lot consistency or confirming biosimilarity.

Developed to exacting specifications, this library complements AdvanceBio Glycan Mapping columns and Agilent’s analytical consumables, providing a critical tool for accurate and reproducible characterization of complex glycan structures. Use it to streamline method validation, ensure regulatory compliance, and achieve robust, dependable results in bioprocessing and biomedical research environments.