Agilent, GKSP-234, AdvanceBio APTS α(2,3) Sialylated tetraantennary N-glycan library (formerly ProZyme)

AdvanceBio APTS α(2,3) Sialylated tetraantennary N-glycan library (formerly ProZyme). Library consists of tetraantennary oligosaccharides containing α(2,3) linked sialic acid. The reducing termini are derivatized with the fluorescent dye, 8-aminopyrene-1,3,6-trisulfonate (APTS) for separation by capillary electrophoresis (CE).

Specifications:
Label: APTS
Unit: 120 pmol

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This highly purified tetraantennary N-glycan library features α(2,3) sialylation and is labeled with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate (APTS), enabling robust and reproducible glycan analysis. The library is ideally suited for use as a reference standard in biopharmaceutical development, glycoprofiling, and quality control workflows to verify chromatographic or electrophoretic methods. It simplifies glycan identification and quantitation when analyzing complex protein glycosylation patterns, critical for ensuring therapeutic protein efficacy and regulatory compliance. Supplied in a ready-to-use format, it supports highly sensitive fluorescence detection and is fully compatible with popular CE-LIF, HPLC, and UPLC systems, including Agilent 2100 Bioanalyzer, Agilent Fragment Analyzer, and other platforms capable of APTS detection. Researchers can leverage this standard to calibrate migration times, assess method performance, and compare glycan profiles across development batches. Designed to meet the rigorous demands of analytical laboratories, the library complements Agilent’s broader AdvanceBio Glycan solutions, integrating seamlessly into established workflows. For upstream or downstream glycan analysis, or for validating sample preparation protocols, this reference set provides confidence in structural assignments of complex biotherapeutic glycosylation.