Agilent, GKSP-262, AdvanceBio APTS α(2,6) Sialylated biantennary N-glycan Library

AdvanceBio APTS α(2,6) Sialylated biantennary N-glycan Library. Library consists of biantennary oligosaccharides containing α(2,6) linked sialic acid. The reducing termini are derivatized with the fluorescent dye, 8-aminopyrene-1,3,6-trisulfonate (APTS), for separation by capillary electrophoresis (CE).

Specifications:
Label: APTS
Unit: 120 pmol

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The AdvanceBio APTS α(2,6) Sialylated Biantennary N-glycan Library offers a reliable, high-purity standard for glycan characterization and quantitation in biopharmaceutical analysis. This library contains well-defined biantennary N-linked glycans with terminal α(2,6)-linked sialic acids, APTS (8-aminopyrene-1,3,6-trisulfonic acid) labeled for optimal fluorescence detection. Designed to streamline method development, system suitability testing, and routine monitoring, it supports researchers in the accurate profiling of glycosylation patterns in monoclonal antibodies, fusion proteins, and glycoproteins.

Applications include glycan mapping, structural elucidation, and quantitative glycoanalysis in development and quality control settings. This reference library is fully compatible with Agilent’s AdvanceBio Glycan Mapping workflow and integrates seamlessly with capillary electrophoresis, UHPLC, and LC-MS platforms equipped for fluorescence or MS detection. Paired with Agilent’s Glycan Analysis kits and analytical columns, it ensures reproducible, sensitive results for regulatory submissions or comparability studies. The product facilitates robust bioprocess and biosimilar development by providing a clear benchmark for complex glycan analysis, reducing variability and enhancing confidence in data quality for critical decision-making in biopharmaceutical research and production.