Agilent, GKSP-264, AdvanceBio APTS α(2,6) Sialylated tetraantennary N-glycan Library

AdvanceBio APTS α(2,6) Sialylated tetraantennary N-glycan Library. Consists of tetraantennary oligosaccharides containing α(2,6) linked sialic acid. The reducing termini are derivatized with the fluorescent dye, 8-aminopyrene-1,3,6-trisulfonate (APTS) for separation by capillary electrophoresis (CE).

Specifications:
Label: APTS
Unit: 120 pmol

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The AdvanceBio APTS α(2,6) Sialylated Tetraantennary N-glycan Library is a highly characterized glycan reference standard designed for advanced glycomics research. This comprehensive library features purified, fully annotated tetraantennary N-glycans carrying α(2,6) sialylation, labeled with 8-aminopyrene-1,3,6-trisulfonic acid (APTS) for superior fluorescent detection sensitivity. It is ideal for use in quantitative and qualitative analyses, method development, and system suitability testing within biopharmaceutical and biotechnological laboratories.

Researchers utilize this glycan library to benchmark performance in high-resolution separation techniques, such as UHPLC with fluorescence detection or capillary electrophoresis, ensuring reproducibility and accuracy in glycan profiling. Its compatibility with Agilent AdvanceBio Glycan Mapping columns and methodologies facilitates streamlined workflows when characterizing complex glycosylation patterns in therapeutic antibodies, recombinant proteins, or biosimilars. The well-defined sialylation and antennary structure provide critical reference data when investigating glycan structural diversity and its impact on biological function.

Seamlessly integrable with Agilent LC systems, CE platforms, and associated software solutions, this library supports comprehensive glycan identification and quantitation. It serves as a trusted control for ensuring regulatory compliance, method validation, and comparative analysis in biopharma analytics, supporting robust and reliable research outcomes.